… channel-forming proteins for antiviral therapy? This review provides an overview of the current
research on viral ion channels … We mainly focus on the ion channels of viruses which can …

… role of ion channels during viral lifecycles, describe the recently identified ion channel drugs
that … that ion channel inhibitors represent a new antiviral strategy. Whilst toxicity profiles for …

… as an antiviral drug target. This review attempts to summarize our current understanding of
the channel-… Ultimately, given the successes of drugs targeting ion channels in other areas of …

… that viral ion channels, in general, may be good targets for the development of antiviral agents,
… of known antiviral phytochemicals on the ionchannel-forming 3a protein of coronavirus. …

… tool to screen drugs for their potency in inhibition of ion channel activity. The viral protein U-…
that viral ion channels, in general, may be a good target for development of antiviral agents, …

… -selective ion channel that is required for virus replication and is an established antiviral target.
… mutations, and ongoing efforts to develop new antivirals that target resistant forms of M2. …

… channel function in vitro and virion production in culture, rendering it an attractive antiviral
target… points26, 27 supports a specific antiviral effect, and selection of specific nonsynonymous …

… These and HIS-tagged p7 function as calcium ion channels in … These homo-oligomerise
to form ion channels and are frequently … them suitable targets for antiviral drug development. …

… viral ion channels, in general, may be a good target for the development of antiviral agents,
and that, in particular, kaempferol glycosides are good candidates for 3a channel proteins of …

… Taken together, the data imply that the antiviral target of HMA is the E protein, and further,
that the E protein ion channel activity is important for coronavirus replication. Other groups …